This study investigates whether treatment with dendritic cells after standard treatment (lymph node toilet or sentinel procedure) is effective in preventing disease recurrence. The efficacy of activating the immune system with dendritic cells is being investigated.
Dendritic cells are extracted from the patient's blood in the laboratory and processed. They are then injected into the lymph nodes to activate the immune system and thereby prevent the disease from coming back.
Autologe dendritische cel vaccinatie versus placebo, ratio 2:1
Leeftijd ≥18 jaar. Start studie binnen 12 weken na lymfeklierdissectie of schildwachtprocedure (in geval van patiënten zonder lymfeklierdissectie gezien minimale schildwachtklier-positieve ziekte). WHO 0-1. Geen auto-immuunziekten of orale of intraveneuze immunosuppressieve medicatie.
- Drs. W. van Willigen, Drs. M. Bloemendal, Dr. K.F. Bol & Prof.dr. W.R. Gerritsen
- MINDstudie.TIL@radboudumc.nl